مرکز توسعه تحقیقات بالینی حضرت علی اصغر (ع)

CRISPR/Cas9 is utilized as a gene editing tool with numerous applications in preventing or treating diseases. It relies on CRISPR as a bacterial immune system to edit genes with high precision and efficiency. The system has been researched for treating various diseases such as cancers, hemolytic diseases, immunodeficiency disorders, and neurodegenerative conditions. It can delete, insert, modify, or block specific genes. Challenges like off-target effects in using CRISPR/Cas9 in vivo, and methods like transfection through viral and non-viral vectors are being explored.

منبع:

https://www.sciencedirect.com/science/article/pii/S235230422300079X